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Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism

INTRODUCTION: Engagement of the homotypic cell-to-cell adhesion molecule cadherin-11 on rheumatoid arthritis (RA) synovial fibroblasts with a chimeric molecule containing the cadherin-11 extracellular binding domain stimulated cytokine, chemokine, and matrix metalloproteinases (MMP) release, implica...

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Detalles Bibliográficos
Autores principales: Noss, Erika H, Watts, Gerald FM, Zocco, Davide, Keller, Tracy L, Whitman, Malcolm, Blobel, Carl P, Lee, David M, Brenner, Michael B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449585/
https://www.ncbi.nlm.nih.gov/pubmed/25975695
http://dx.doi.org/10.1186/s13075-015-0647-9