Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity

Pancreatic β cells secrete insulin in order to maintain glucose homeostasis. However, various environmental stresses such as obesity have been shown to induce loss of secretory responsiveness in pancreatic β cells and pancreatic β cell apoptosis which can favor the development of type 2 diabetes (T2...

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Detalles Bibliográficos
Autores principales: Véret, Julien, Bellini, Lara, Giussani, Paola, Ng, Carl, Magnan, Christophe, Le Stunff, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449690/
https://www.ncbi.nlm.nih.gov/pubmed/26237395
http://dx.doi.org/10.3390/jcm3020646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449690/
https://www.ncbi.nlm.nih.gov/pubmed/26237395
http://dx.doi.org/10.3390/jcm3020646

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