Clonotypically similar hybrid αβ T cell receptors can exhibit markedly different surface expression, antigen specificity and cross‐reactivity

Emerging data indicate that particular major histocompatibility complex (MHC)‐bound antigenic peptides can be recognized by identical or near‐identical αβ T cell receptors (TCRs) in different individuals. To establish the functional relevance of this phenomenon, we artificially paired α and β chains...

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Detalles Bibliográficos
Autores principales: Motozono, C., Bridgeman, J. S., Price, D. A., Sewell, A. K., Ueno, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Translation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449784/
https://www.ncbi.nlm.nih.gov/pubmed/25721491
http://dx.doi.org/10.1111/cei.12610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449784/
https://www.ncbi.nlm.nih.gov/pubmed/25721491
http://dx.doi.org/10.1111/cei.12610

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