Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis

MicroRNAs, activated by the enzyme Dicer1, control post-transcriptional gene expression. Dicer1 has important roles in the epithelium during nephrogenesis, but its function in stromal cells during kidney development is unknown. To study this we inactivated Dicer1 in renal stromal cells. This resulte...

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Detalles Bibliográficos
Autores principales: Nakagawa, Naoki, Xin, Cuiyan, Roach, Allie M., Naiman, Natalie, Shankland, Stuart J., Ligresti, Giovanni, Ren, Shuyu, Szak, Suzanne, Gomez, Ivan G., Duffield, Jeremy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449790/
https://www.ncbi.nlm.nih.gov/pubmed/25651362
http://dx.doi.org/10.1038/ki.2014.406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449790/
https://www.ncbi.nlm.nih.gov/pubmed/25651362
http://dx.doi.org/10.1038/ki.2014.406

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