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Differential expression and regulation of Klotho by paricalcitol in the kidney, parathyroid and aorta of uremic rats

Klotho plays an important role in the pathogenesis of cardiovascular disease in chronic kidney disease (CKD). Klotho is highly expressed in the kidney and parathyroid glands, but its presence in the vasculature is debated. Renal Klotho is decreased in CKD, but the effect of uremia on Klotho in other...

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Detalles Bibliográficos
Autores principales: Ritter, Cynthia S., Zhang, Sarah, Delmez, James, Finch, Jane L, Slatopolsky, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449811/
https://www.ncbi.nlm.nih.gov/pubmed/25692955
http://dx.doi.org/10.1038/ki.2015.22