Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis

Chaperone-mediated autophagy (CMA) selectively degrades a subset of cytosolic proteins in lysosomes. A potent physiological activator of CMA is nutrient deprivation, a condition in which intracellular triglyceride stores or lipid droplets (LD) also undergo hydrolysis (lipolysis) to generate free fat...

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Detalles Bibliográficos
Autores principales: Kaushik, Susmita, Cuervo, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449813/
https://www.ncbi.nlm.nih.gov/pubmed/25961502
http://dx.doi.org/10.1038/ncb3166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449813/
https://www.ncbi.nlm.nih.gov/pubmed/25961502
http://dx.doi.org/10.1038/ncb3166

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