Deguelin Induces Apoptosis by Targeting Both EGFR-Akt and IGF1R-Akt Pathways in Head and Neck Squamous Cell Cancer Cell Lines

Deguelin, a rotenoid compound from the African plant Mundulea sericea (Leguminosae), has been shown to possess antitumor activities but the exact role for the growth factor receptor mediated signaling pathway in head and neck squamous cell carcinoma (HNSCC) is currently still unclear. In the present...

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Detalles Bibliográficos
Autores principales: Baba, Yuh, Fujii, Masato, Maeda, Toyonobu, Suzuki, Atsuko, Yuzawa, Satoshi, Kato, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449895/
https://www.ncbi.nlm.nih.gov/pubmed/26075254
http://dx.doi.org/10.1155/2015/657179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449895/
https://www.ncbi.nlm.nih.gov/pubmed/26075254
http://dx.doi.org/10.1155/2015/657179

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