Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

BACKGROUND: To evaluate the role of NADPH oxidase-mediated reactive oxygen species (ROS) production in multiple sclerosis pathogenesis, we examined the effects of apocynin, an NADPH oxidase assembly inhibitor, on experimental autoimmune encephalomyelitis (EAE). METHODS: EAE was induced by immunizati...

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Detalles Bibliográficos
Autores principales: Choi, Bo Young, Kim, Jin Hee, Kho, A Ra, Kim, In Yeol, Lee, Song Hee, Lee, Bo Eun, Choi, Eunhi, Sohn, Min, Stevenson, Mackenzie, Chung, Tae Nyoung, Kauppinen, Tiina M, Suh, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449958/
https://www.ncbi.nlm.nih.gov/pubmed/26017142
http://dx.doi.org/10.1186/s12974-015-0325-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449958/
https://www.ncbi.nlm.nih.gov/pubmed/26017142
http://dx.doi.org/10.1186/s12974-015-0325-5

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