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Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice

BACKGROUND: To evaluate the role of NADPH oxidase-mediated reactive oxygen species (ROS) production in multiple sclerosis pathogenesis, we examined the effects of apocynin, an NADPH oxidase assembly inhibitor, on experimental autoimmune encephalomyelitis (EAE). METHODS: EAE was induced by immunizati...

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Detalles Bibliográficos
Autores principales:	Choi, Bo Young, Kim, Jin Hee, Kho, A Ra, Kim, In Yeol, Lee, Song Hee, Lee, Bo Eun, Choi, Eunhi, Sohn, Min, Stevenson, Mackenzie, Chung, Tae Nyoung, Kauppinen, Tiina M, Suh, Sang Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449958/ https://www.ncbi.nlm.nih.gov/pubmed/26017142 http://dx.doi.org/10.1186/s12974-015-0325-5

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