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Acid-sensing ion channels: potential therapeutic targets for neurologic diseases

Maintaining the physiological pH of interstitial fluid is crucial for normal cellular functions. In disease states, tissue acidosis is a common pathologic change causing abnormal activation of acid-sensing ion channels (ASICs), which according to cumulative evidence, significantly contributes to inf...

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Detalles Bibliográficos
Autores principales: Liu, Sha, Cheng, Xiao-Yu, Wang, Fen, Liu, Chun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449961/
https://www.ncbi.nlm.nih.gov/pubmed/26029363
http://dx.doi.org/10.1186/s40035-015-0031-3