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Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells

Genes or their encoded products are not expected to mingle with each other unless in some disease situations. In cancer, a frequent mechanism that can produce gene fusions is chromosomal rearrangement. However, recent discoveries of RNA trans-splicing and cis-splicing between adjacent genes (cis-SAG...

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Detalles Bibliográficos
Autores principales: Qin, Fujun, Song, Zhenguo, Babiceanu, Mihaela, Song, Yansu, Facemire, Loryn, Singh, Ritambhara, Adli, Mazhar, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450057/
https://www.ncbi.nlm.nih.gov/pubmed/25658338
http://dx.doi.org/10.1371/journal.pgen.1005001