A Membrane-bound eIF2 Alpha Kinase Located in Endosomes Is Regulated by Heme and Controls Differentiation and ROS Levels in Trypanosoma cruzi

Translation initiation has been described as a key step for the control of growth and differentiation of several protozoan parasites in response to environmental changes. This occurs by the activation of protein kinases that phosphorylate the alpha subunit of the translation initiation factor 2 (eIF...

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Detalles Bibliográficos
Autores principales: da Silva Augusto, Leonardo, Moretti, Nilmar Silvio, Ramos, Thiago Cesar Prata, de Jesus, Teresa Cristina Leandro, Zhang, Min, Castilho, Beatriz A., Schenkman, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450062/
https://www.ncbi.nlm.nih.gov/pubmed/25658109
http://dx.doi.org/10.1371/journal.ppat.1004618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450062/
https://www.ncbi.nlm.nih.gov/pubmed/25658109
http://dx.doi.org/10.1371/journal.ppat.1004618

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