Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice

The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense strategies. We show that disruption of M. tuberculosis membrane protein PerM (Rv0955) resulted in an IFN-γ-dependent persistence defect in chronic...

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Detalles Bibliográficos
Autores principales: Goodsmith, Nichole, Guo, Xinzheng V., Vandal, Omar H., Vaubourgeix, Julien, Wang, Ruojun, Botella, Hélène, Song, Shuang, Bhatt, Kamlesh, Liba, Amir, Salgame, Padmini, Schnappinger, Dirk, Ehrt, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450064/
https://www.ncbi.nlm.nih.gov/pubmed/25658098
http://dx.doi.org/10.1371/journal.ppat.1004645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450064/
https://www.ncbi.nlm.nih.gov/pubmed/25658098
http://dx.doi.org/10.1371/journal.ppat.1004645

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