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Cytoplasmic Actin Is an Extracellular Insect Immune Factor which Is Secreted upon Immune Challenge and Mediates Phagocytosis and Direct Killing of Bacteria, and Is a Plasmodium Antagonist

Actin is a highly versatile, abundant, and conserved protein, with functions in a variety of intracellular processes. Here, we describe a novel role for insect cytoplasmic actin as an extracellular pathogen recognition factor that mediates antibacterial defense. Insect actins are secreted from cells...

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Detalles Bibliográficos
Autores principales: Sandiford, Simone L., Dong, Yuemei, Pike, Andrew, Blumberg, Benjamin J., Bahia, Ana C., Dimopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450071/
https://www.ncbi.nlm.nih.gov/pubmed/25658622
http://dx.doi.org/10.1371/journal.ppat.1004631