Manipulating Adenovirus Hexon Hypervariable Loops Dictates Immune Neutralisation and Coagulation Factor X-dependent Cell Interaction In Vitro and In Vivo

Adenoviruses are common pathogens, mostly targeting ocular, gastrointestinal and respiratory cells, but in some cases infection disseminates, presenting in severe clinical outcomes. Upon dissemination and contact with blood, coagulation factor X (FX) interacts directly with the adenovirus type 5 (Ad...

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Detalles Bibliográficos
Autores principales: Ma, Jiangtao, Duffy, Margaret R., Deng, Lin, Dakin, Rachel S., Uil, Taco, Custers, Jerome, Kelly, Sharon M., McVey, John H., Nicklin, Stuart A., Baker, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450073/
https://www.ncbi.nlm.nih.gov/pubmed/25658827
http://dx.doi.org/10.1371/journal.ppat.1004673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450073/
https://www.ncbi.nlm.nih.gov/pubmed/25658827
http://dx.doi.org/10.1371/journal.ppat.1004673

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