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Mannosylated Linear and Cyclic Single Amino Acid Mutant Peptides Using a Small 10 Amino Acid Linker Constitute Promising Candidates Against Multiple Sclerosis

Multiple sclerosis (MS) is a serious autoimmune demyelinating disease leading to loss of neurological function. The design and synthesis of various altered peptide ligands of immunodominant epitopes of myelin proteins to alter the autoimmune response, is a promising therapeutic approach for MS. In t...

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Detalles Bibliográficos
Autores principales: Day, Stephanie, Tselios, Theodore, Androutsou, Maria-Eleni, Tapeinou, Anthi, Frilligou, Irene, Stojanovska, Lily, Matsoukas, John, Apostolopoulos, Vasso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450228/
https://www.ncbi.nlm.nih.gov/pubmed/26082772
http://dx.doi.org/10.3389/fimmu.2015.00136