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The oncogenic role of the cochaperone Sgt1

Sgt1/Sugt1, a cochaperone of Hsp90, is involved in several cellular activities including Cullin E3 ubiqutin ligase activity. The high level of Sgt1 expression in colorectal and gastric tumors suggests that Sgt1 is involved in tumorigenesis. Here, we report that Sgt1 is overexpressed in colon, breast...

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Detalles Bibliográficos
Autores principales: Ogi, H, Sakuraba, Y, Kitagawa, R, Xiao, L, Shen, C, Cynthia, M A, Ohta, S, Arnold, M A, Ramirez, N, Houghton, P J, Kitagawa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450263/
https://www.ncbi.nlm.nih.gov/pubmed/25985210
http://dx.doi.org/10.1038/oncsis.2015.12