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Structural constraints on the evolution of the collagen fibril: convergence on a 1014-residue COL domain
Type I collagen is the fundamental component of the extracellular matrix. Its α1 gene is the direct descendant of ancestral fibrillar collagen and contains 57 exons encoding the rod-like triple-helical COL domain. We trace the evolution of the COL domain from a primordial collagen 18 residues in len...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450265/ https://www.ncbi.nlm.nih.gov/pubmed/25994354 http://dx.doi.org/10.1098/rsob.140220 |