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The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity

Different tissues contain diverse and dynamic cellular niches, providing distinct signals to tissue-resident or migratory infiltrating immune cells. Hedgehog (Hh) proteins are secreted inter-cellular signalling molecules, which are essential during development and are important in cancer, post-natal...

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Detalles Bibliográficos
Autores principales: Furmanski, Anna L., Barbarulo, Alessandro, Solanki, Anisha, Lau, Ching-In, Sahni, Hemant, Saldana, Jose Ignacio, D'Acquisto, Fulvio, Crompton, Tessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450292/
https://www.ncbi.nlm.nih.gov/pubmed/25908851
http://dx.doi.org/10.1242/jcs.165803