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Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration

Bone marrow-derived mesenchymal stromal cells (BM-MSCs) play a fundamental role in the BM microenvironment (BME) and abnormalities of these cells may contribute to acute myeloid leukemia (AML) pathogenesis. The aim of the study was to characterize the cytokine and gene expression profile, immunophen...

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Detalles Bibliográficos
Autores principales: Huang, J C, Basu, S K, Zhao, X, Chien, S, Fang, M, Oehler, V G, Appelbaum, F R, Becker, P S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450324/
https://www.ncbi.nlm.nih.gov/pubmed/25860293
http://dx.doi.org/10.1038/bcj.2015.17