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Mesenchymal stromal cells derived from acute myeloid leukemia bone marrow exhibit aberrant cytogenetics and cytokine elaboration
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) play a fundamental role in the BM microenvironment (BME) and abnormalities of these cells may contribute to acute myeloid leukemia (AML) pathogenesis. The aim of the study was to characterize the cytokine and gene expression profile, immunophen...
Autores principales: | Huang, J C, Basu, S K, Zhao, X, Chien, S, Fang, M, Oehler, V G, Appelbaum, F R, Becker, P S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450324/ https://www.ncbi.nlm.nih.gov/pubmed/25860293 http://dx.doi.org/10.1038/bcj.2015.17 |
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