Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia

To find drugs suitable for repositioning for use against leukemia, samples from patients with chronic lymphocytic, acute myeloid and lymphocytic leukemias as well as peripheral blood mononuclear cells (PBMC) were tested in response to 1266 compounds from the LOPAC(1280) library (Sigma). Twenty-five...

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Detalles Bibliográficos
Autores principales: Eriksson, A, Österroos, A, Hassan, S, Gullbo, J, Rickardson, L, Jarvius, M, Nygren, P, Fryknäs, M, Höglund, M, Larsson, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450329/
https://www.ncbi.nlm.nih.gov/pubmed/25885427
http://dx.doi.org/10.1038/bcj.2015.31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450329/
https://www.ncbi.nlm.nih.gov/pubmed/25885427
http://dx.doi.org/10.1038/bcj.2015.31

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