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Excellent response of intramedullary Erdheim-Chester disease to vemurafenib: a case report

BACKGROUND: Erdheim-Chester disease is a rare histiocytosis characterized by multi-systemic organ involvement. Immune-modulating agents such as interferon-alpha have limited success and the disorder is progressive and causes high morbidity and mortality. Treatment with the BRAF-inhibitor vemurafenib...

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Detalles Bibliográficos
Autores principales: Tzoulis, Charalampos, Schwarzlmüller, Thomas, Gjerde, Ivar Otto, Søfteland, Eirik, Neckelmann, Gesche, Biermann, Martin, Haroche, Julien, Straume, Oddbjørn, Vintermyr, Olav Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450489/
https://www.ncbi.nlm.nih.gov/pubmed/25926131
http://dx.doi.org/10.1186/s13104-015-1135-7