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Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase

BACKGROUND: Uracil-DNA glycosylases are evolutionarily conserved DNA repair enzymes. However, vaccinia virus uracil-DNA glycosylase (known as D4), also serves as an intrinsic and essential component of the processive DNA polymerase complex during DNA replication. In this complex D4 binds to a unique...

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Detalles Bibliográficos
Autores principales: Schormann, Norbert, Banerjee, Surajit, Ricciardi, Robert, Chattopadhyay, Debasish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450493/
https://www.ncbi.nlm.nih.gov/pubmed/26031450
http://dx.doi.org/10.1186/s12900-015-0037-1