In silico analysis of potential inhibitors of Ca(2+) activated K(+) channel blocker, Charybdotoxin-C from Leiurus quinquestriatus hebraeus through molecular docking and dynamics studies

OBJECTIVE: Charybdotoxin-C (ChTx-C), from the scorpion Leiurus, quinquestriatus hebraeus blocks the calcium-activated potassium channels and causes hyper excitability of the nervous system. Detailed understanding the structure of ChTx-C, conformational stability, and intermolecular interactions are...

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Detalles Bibliográficos
Autores principales: Kumar, R. Barani, Priya, B. Shanmuga, Suresh, M. Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450553/
https://www.ncbi.nlm.nih.gov/pubmed/26069365
http://dx.doi.org/10.4103/0253-7613.157123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450553/
https://www.ncbi.nlm.nih.gov/pubmed/26069365
http://dx.doi.org/10.4103/0253-7613.157123

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