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The FAD-dependent glycerol-3-phosphate dehydrogenase of Giardia duodenalis: an unconventional enzyme that interacts with the g14-3-3 and it is a target of the antitumoral compound NBDHEX

The flagellated protozoan Giardia duodenalis is a worldwide parasite causing giardiasis, an acute and chronic diarrheal disease. Metabolism in G. duodenalis has a limited complexity thus making metabolic enzymes ideal targets for drug development. However, only few metabolic pathways (i.e., carbohyd...

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Detalles Bibliográficos
Autores principales: Lalle, Marco, Camerini, Serena, Cecchetti, Serena, Finelli, Renata, Sferra, Gabriella, Müller, Joachim, Ricci, Giorgio, Pozio, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450592/
https://www.ncbi.nlm.nih.gov/pubmed/26082764
http://dx.doi.org/10.3389/fmicb.2015.00544