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The FAD-dependent glycerol-3-phosphate dehydrogenase of Giardia duodenalis: an unconventional enzyme that interacts with the g14-3-3 and it is a target of the antitumoral compound NBDHEX
The flagellated protozoan Giardia duodenalis is a worldwide parasite causing giardiasis, an acute and chronic diarrheal disease. Metabolism in G. duodenalis has a limited complexity thus making metabolic enzymes ideal targets for drug development. However, only few metabolic pathways (i.e., carbohyd...
Autores principales: | Lalle, Marco, Camerini, Serena, Cecchetti, Serena, Finelli, Renata, Sferra, Gabriella, Müller, Joachim, Ricci, Giorgio, Pozio, Edoardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450592/ https://www.ncbi.nlm.nih.gov/pubmed/26082764 http://dx.doi.org/10.3389/fmicb.2015.00544 |
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