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SLCO1B1 Polymorphism is not associated with Risk of Statin-Induced Myalgia/Myopathy in a Czech Population

BACKGROUND: Gene SLCO1B1, encoding solute organic anionic transport polypeptide OATP1B1, belongs to the group of candidates potentially influencing statin treatment safety. OATP1B1 regulates (not only) the hepatic uptake of statins. Its genetic variation was described as an important predictor of st...

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Detalles Bibliográficos
Autores principales: Hubáček, Jaroslav A., Dlouhá, Dana, Adámková, Vera, Zlatohlávek, Lukáš, Viklický, Ondřej, Hrubá, Petra, Češka, Richard, Vrablík, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450600/
https://www.ncbi.nlm.nih.gov/pubmed/25992810
http://dx.doi.org/10.12659/MSM.893007