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Does Insulin Like Growth Factor-1 (IGF-1) Deficiency Have a “Protective” Role in the Development of Diabetic Retinopathy in Thalassamia Major Patients?

RATIONALE: Both insulin and IGF-1 have been implicated in the control of retinal endothelial cell growth, neovascularization and diabetic retinopathy. Recent findings have established an essential role for IGF-1 in angiogenesis and demonstrated a new target for control of retinopathy that explains w...

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Detalles Bibliográficos
Autores principales: De Sanctis, Vincenzo, Incorvaia, Carlo, Soliman, Ashraf T, Candini, Giancarlo, Pepe, Alessia, Kattamis, Christos, Soliman, Nada A., Elsedfy, Heba, Kholy, Mohamed El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450649/
https://www.ncbi.nlm.nih.gov/pubmed/26075045
http://dx.doi.org/10.4084/MJHID.2015.038