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Good Outcome for Very High Risk Adult B-cell Acute Lymphoblastic Leukaemia Carrying Genetic Abnormalities t(4;11)(q21;q23) or t(9;22)(q34;q11), if Promptly Submitted to Allogeneic Transplantation, after Obtaining a Good Molecular Remission

BACKGROUND AND OBJECTIVES: Acute lymphoblastic leukaemia (ALL) carrying t(9;22) or t(4;11) genetic abnormalities represents a very high risk subtype of disease (VHR-ALL). Hematopoietic stem cell transplantation (HSCT) remains the best curative option not only for t(4;11) ALL, but also for t(9;22) AL...

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Detalles Bibliográficos
Autores principales: Parma, Matteo, Viganò, Clara, Fumagalli, Monica, Colnaghi, Federica, Colombo, Arianna, Mottadelli, Federica, Rossi, Vincenzo, Elli, Elena, Terruzzi, Elisabetta, Belotti, Angelo, Cazzaniga, Giovanni, Pogliani, Enrico Maria, Pioltelli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450652/
https://www.ncbi.nlm.nih.gov/pubmed/26075048
http://dx.doi.org/10.4084/MJHID.2015.041