The Wnt5a-Ror2 axis promotes the signaling circuit between interleukin-12 and interferon-γ in colitis

Wnt5a, which regulates various cellular functions in Wnt signaling, is involved in inflammatory responses, however the mechanism is not well understood. We examined the role of Wnt5a signaling in intestinal immunity using conditional knockout mice for Wnt5a and its receptor Ror2. Removing Wnt5a or R...

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Detalles Bibliográficos
Autores principales: Sato, Akira, Kayama, Hisako, Shojima, Kensaku, Matsumoto, Shinji, Koyama, Hirofumi, Minami, Yasuhiro, Nojima, Satoshi, Morii, Eiichi, Honda, Hiroaki, Takeda, Kiyoshi, Kikuchi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450756/
https://www.ncbi.nlm.nih.gov/pubmed/26030277
http://dx.doi.org/10.1038/srep10536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450756/
https://www.ncbi.nlm.nih.gov/pubmed/26030277
http://dx.doi.org/10.1038/srep10536

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