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Placement of oppositely charged aminoacids at a polypeptide termini determines the voltage-controlled braking of polymer transport through nanometer-scale pores

Protein and solid-state nanometer-scale pores are being developed for the detection, analysis, and manipulation of single molecules. In the simplest embodiment, the entry of a molecule into a nanopore causes a reduction in the latter’s ionic conductance. The ionic current blockade depth and residenc...

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Detalles Bibliográficos
Autores principales: Asandei, Alina, Chinappi, Mauro, Lee, Jong-kook, Ho Seo, Chang, Mereuta, Loredana, Park, Yoonkyung, Luchian, Tudor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450769/
https://www.ncbi.nlm.nih.gov/pubmed/26029865
http://dx.doi.org/10.1038/srep10419