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Activation of peripheral KCNQ channels relieves gout pain

Intense inflammatory pain caused by urate crystals in joints and other tissues is a major symptom of gout. Among therapy drugs that lower urate, benzbromarone (BBR), an inhibitor of urate transporters, is widely used because it is well tolerated and highly effective. We demonstrate that BBR is also...

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Detalles Bibliográficos
Autores principales: Zheng, Yueming, Xu, Haiyan, Zhan, Li, Zhou, Xindi, Chen, Xueqin, Gao, Zhaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450870/
https://www.ncbi.nlm.nih.gov/pubmed/25735002
http://dx.doi.org/10.1097/j.pain.0000000000000122