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Activation of peripheral KCNQ channels relieves gout pain
Intense inflammatory pain caused by urate crystals in joints and other tissues is a major symptom of gout. Among therapy drugs that lower urate, benzbromarone (BBR), an inhibitor of urate transporters, is widely used because it is well tolerated and highly effective. We demonstrate that BBR is also...
Autores principales: | Zheng, Yueming, Xu, Haiyan, Zhan, Li, Zhou, Xindi, Chen, Xueqin, Gao, Zhaobing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450870/ https://www.ncbi.nlm.nih.gov/pubmed/25735002 http://dx.doi.org/10.1097/j.pain.0000000000000122 |
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