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Phosphorus-32, a Clinically Available Drug, Inhibits Cancer Growth by Inducing DNA Double-Strand Breakage

Radioisotopes that emit electrons (beta particles), such as radioiodine, can effectively kill target cells, including cancer cells. Aqueous (32)P[PO(4)] is a pure beta-emitter that has been used for several decades to treat non-malignant human myeloproliferative diseases. (32)P[PO(4)] was directly c...

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Detalles Bibliográficos
Autores principales: Cheng, Yulan, Kiess, Ana P., Herman, Joseph M., Pomper, Martin G., Meltzer, Stephen J., Abraham, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450878/
https://www.ncbi.nlm.nih.gov/pubmed/26030880
http://dx.doi.org/10.1371/journal.pone.0128152