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Monocyte and M1 Macrophage-induced Barrier Defect Contributes to Chronic Intestinal Inflammation in IBD

BACKGROUND: Macrophages are key players in inflammatory bowel diseases (IBD). This study aimed to determine site-specific effects of defined macrophage subtypes on the integrity of the intestinal epithelial barrier. METHODS: Macrophage subtypes in situ in intestinal specimens of patients with IBD we...

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Detalles Bibliográficos
Autores principales: Lissner, Donata, Schumann, Michael, Batra, Arvind, Kredel, Lea-Isabel, Kühl, Anja A., Erben, Ulrike, May, Claudia, Schulzke, Jörg-Dieter, Siegmund, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450953/
https://www.ncbi.nlm.nih.gov/pubmed/25901973
http://dx.doi.org/10.1097/MIB.0000000000000384