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Increased robustness of early embryogenesis through collective decision-making by key transcription factors
BACKGROUND: Understanding the mechanisms by which hundreds of diverse cell types develop from a single mammalian zygote has been a central challenge of developmental biology. Conrad H. Waddington, in his metaphoric “epigenetic landscape” visualized the early embryogenesis as a hierarchy of lineage b...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450992/ https://www.ncbi.nlm.nih.gov/pubmed/26033487 http://dx.doi.org/10.1186/s12918-015-0169-8 |