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Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment

BACKGROUND: To understand the heterogeneous behaviors of individual cancer cells, it is essential to investigate gene expression levels as well as their divergence between different individual cells. Recent advances in next-generation sequencing-related technologies have enabled us to conduct a sing...

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Detalles Bibliográficos
Autores principales: Suzuki, Ayako, Matsushima, Koutatsu, Makinoshima, Hideki, Sugano, Sumio, Kohno, Takashi, Tsuchihara, Katsuya, Suzuki, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450998/
https://www.ncbi.nlm.nih.gov/pubmed/25887790
http://dx.doi.org/10.1186/s13059-015-0636-y