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Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment
BACKGROUND: To understand the heterogeneous behaviors of individual cancer cells, it is essential to investigate gene expression levels as well as their divergence between different individual cells. Recent advances in next-generation sequencing-related technologies have enabled us to conduct a sing...
Autores principales: | Suzuki, Ayako, Matsushima, Koutatsu, Makinoshima, Hideki, Sugano, Sumio, Kohno, Takashi, Tsuchihara, Katsuya, Suzuki, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450998/ https://www.ncbi.nlm.nih.gov/pubmed/25887790 http://dx.doi.org/10.1186/s13059-015-0636-y |
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