Vorinostat enhances chemosensitivity to arsenic trioxide in K562 cell line

Objective. This study aimed to investigate the chemosensitive augmentation effect and mechanism of HDAC inhibitor Vorinostat (SAHA) in combination with arsenic trioxide (ATO) on proliferation and apoptosis of K562 cells. Methods. The CCK-8 assay was used to compare proliferation of the cells. Annexi...

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Detalles Bibliográficos
Autores principales: Li, Nainong, Guan, Xiaoyan, Li, Fang, Li, Xiaofan, Chen, Yuanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451029/
https://www.ncbi.nlm.nih.gov/pubmed/26038719
http://dx.doi.org/10.7717/peerj.962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451029/
https://www.ncbi.nlm.nih.gov/pubmed/26038719
http://dx.doi.org/10.7717/peerj.962

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