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A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody

The CCR5 receptor plays a role in several key physiological and pathological processes and is an important therapeutic target. Inhibition of the CCR5 axis by passive or active immunisation offers one very selective strategy for intervention. In this study we define a new linear epitope within the ex...

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Detalles Bibliográficos
Autores principales: Chain, Benny, Arnold, Jack, Akthar, Samia, Brandt, Michael, Davis, David, Noursadeghi, Mahdad, Lapp, Thabo, Ji, Changhua, Sankuratri, Surya, Zhang, Yanjing, Govada, Lata, Saridakis, Emmanuel, Chayen, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451072/
https://www.ncbi.nlm.nih.gov/pubmed/26030924
http://dx.doi.org/10.1371/journal.pone.0128381