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IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

The most studied biological role of type III interferons (IFNs) has so far been their antiviral activity, but their role in autoimmune and inflammatory diseases remains largely unexplored. Here, we show that treatment with IFN-λ2/IL-28A completely halts and reverses the development of collagen-induc...

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Detalles Bibliográficos
Autores principales: Blazek, Katrina, Eames, Hayley L., Weiss, Miriam, Byrne, Adam J., Perocheau, Dany, Pease, James E., Doyle, Sean, McCann, Fiona, Williams, Richard O., Udalova, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451128/
https://www.ncbi.nlm.nih.gov/pubmed/25941255
http://dx.doi.org/10.1084/jem.20140995