Cargando…

Stathmin Potentiates Vinflunine and Inhibits Paclitaxel Activity

Cell biology and crystallographic studies have suggested a functional link between stathmin and microtubule targeting agents (MTAs). In a previous study we showed that stathmin increases vinblastine (VLB) binding to tubulin, and that conversely VLB increases stathmin binding to tubulin. This constit...

Descripción completa

Detalles Bibliográficos
Autores principales: Malesinski, Soazig, Tsvetkov, Philipp O., Kruczynski, Anna, Peyrot, Vincent, Devred, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451147/
https://www.ncbi.nlm.nih.gov/pubmed/26030092
http://dx.doi.org/10.1371/journal.pone.0128704