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MicroRNA-Mediated In Vitro and In Vivo Direct Conversion of Astrocytes to Neuroblasts
BACKGROUND: The conversion of astrocytes to neuroblasts holds great promise for treatment of neurodegenerative and traumatic brain diseases. METHODOLOGY AND PRINCIPAL FINDINGS: Here we have shown that adult human astrocytes could be reprogrammed to neuroblasts by miR-302/367, both in vivo and in vit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451260/ https://www.ncbi.nlm.nih.gov/pubmed/26030913 http://dx.doi.org/10.1371/journal.pone.0127878 |