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MicroRNA-Mediated In Vitro and In Vivo Direct Conversion of Astrocytes to Neuroblasts

BACKGROUND: The conversion of astrocytes to neuroblasts holds great promise for treatment of neurodegenerative and traumatic brain diseases. METHODOLOGY AND PRINCIPAL FINDINGS: Here we have shown that adult human astrocytes could be reprogrammed to neuroblasts by miR-302/367, both in vivo and in vit...

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Detalles Bibliográficos
Autores principales:	Ghasemi-Kasman, Maryam, Hajikaram, Maryam, Baharvand, Hossein, Javan, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451260/ https://www.ncbi.nlm.nih.gov/pubmed/26030913 http://dx.doi.org/10.1371/journal.pone.0127878

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