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TGF-β-induced IL-6 prevents development of acute lung injury in influenza A virus-infected F508del CFTR-heterozygous mice

As the eighth leading cause of annual mortality in the USA, influenza A viruses are a major public health concern. In 20% of patients, severe influenza progresses to acute lung injury (ALI). However, pathophysiological mechanisms underlying ALI development are poorly defined. We reported that, unlik...

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Detalles Bibliográficos
Autores principales: Woods, Parker S., Tazi, Mia F., Chesarino, Nicholas M., Amer, Amal O., Davis, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451396/
https://www.ncbi.nlm.nih.gov/pubmed/25840995
http://dx.doi.org/10.1152/ajplung.00078.2015