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Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol

Growing evidence indicates that the endocannabinoid system is important for the acquisition and/or extinction of learning and memory. However, it is unclear which endocannabinoid(s) play(s) a crucial role in these cognitive functions, especially memory extinction. To elucidate the physiological role...

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Detalles Bibliográficos
Autores principales: Kishimoto, Yasushi, Cagniard, Barbara, Yamazaki, Maya, Nakayama, Junko, Sakimura, Kenji, Kirino, Yutaka, Kano, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451424/
https://www.ncbi.nlm.nih.gov/pubmed/26082696
http://dx.doi.org/10.3389/fnbeh.2015.00134