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The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’ phenotype in response to Th2 immunologic challenge

Tissue resident macrophages have vital homeostatic roles in many tissues but their roles are less well defined in the heart. The present study aimed to identify the density, polarisation status and distribution of macrophages in the healthy murine heart and to investigate their ability to respond to...

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Detalles Bibliográficos
Autores principales: Mylonas, Katie J., Jenkins, Stephen J., Castellan, Raphael F.P., Ruckerl, Dominik, McGregor, Kieran, Phythian-Adams, Alexander T., Hewitson, James P., Campbell, Sharon M., MacDonald, Andrew S., Allen, Judith E., Gray, Gillian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451497/
https://www.ncbi.nlm.nih.gov/pubmed/25700973
http://dx.doi.org/10.1016/j.imbio.2015.01.013