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The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an ‘M2’ phenotype in response to Th2 immunologic challenge
Tissue resident macrophages have vital homeostatic roles in many tissues but their roles are less well defined in the heart. The present study aimed to identify the density, polarisation status and distribution of macrophages in the healthy murine heart and to investigate their ability to respond to...
Autores principales: | Mylonas, Katie J., Jenkins, Stephen J., Castellan, Raphael F.P., Ruckerl, Dominik, McGregor, Kieran, Phythian-Adams, Alexander T., Hewitson, James P., Campbell, Sharon M., MacDonald, Andrew S., Allen, Judith E., Gray, Gillian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451497/ https://www.ncbi.nlm.nih.gov/pubmed/25700973 http://dx.doi.org/10.1016/j.imbio.2015.01.013 |
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