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9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

The retinoid X receptors (RXRs) are ligand-activated transcription factors which heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of (patho)-physiological processes. Although synthetic RXR ligands are developed for the treatment of various diseases, endogenous...

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Detalles Bibliográficos
Autores principales: Rühl, Ralph, Krzyżosiak, Agnieszka, Niewiadomska-Cimicka, Anna, Rochel, Natacha, Szeles, Lajos, Vaz, Belén, Wietrzych-Schindler, Marta, Álvarez, Susana, Szklenar, Monika, Nagy, Laszlo, de Lera, Angel R., Krężel, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451509/
https://www.ncbi.nlm.nih.gov/pubmed/26030625
http://dx.doi.org/10.1371/journal.pgen.1005213